Hematological effects reported following use of isoniazid include various anemias, agranulocytosis, thrombocytopenia and eosinophilia.
Other adverse effects include nausea, vomiting, pellagra, purpura, hyperglycemia, lupus-like syndrome, urinary retention and gynecomastia.
Treatment of Adverse Effects: Pyridoxine HCl 10 mg daily has been recommended to prophylaxis of peripheral neuritis associated with isoniazid although some have suggested using up to 50 mg daily.
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